N-acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study.

Fabiano G NeryMaxwell J TallmanKim M CecilThomas J BlomLuis R PatinoCaleb M AdlerMelissa P DelBello

Published in: Early intervention in psychiatry (2021)

This pilot study suggests that NAC might be efficacious for depressive symptoms in at-risk youth, and that its mechanism of action involves the modulation of glutamate in the left VLPFC.

Keyphrases

prefrontal cortex
depressive symptoms
bipolar disorder
major depressive disorder
sleep quality
social support
transcription factor
mental health
physical activity
young adults