High glutamic acid decarboxylase antibody titers may be associated with a decline in β-cell function over time and future insulin deficiency in latent autoimmune diabetes in adults.
Akifumi HaisaYoichi OikawaAtsushi SatomuraSeiya SuzukiShumpei NakanishiMasashi FujisawaHideo MoritaTakeshi KatsukiAkira ShimadaPublished in: Diabetes research and clinical practice (2024)
GADA-ELISA titer of ≥180 U/mL, especially with HLA-DRB1*04:05, might reflect higher disease activity and may be associated with decline in β-cell function over time and future insulin dependency in LADA.