The Effect of a Loading Dose Regimen in the Switch to Brolucizumab for Patients with Aflibercept-Resistant nAMD.

Hiroyuki KamaoErika MitsuiYuto DateKatsutoshi GotoKenichi MizukawaAtsushi Miki

Published in: Journal of ophthalmology (2024)

Switching to brolucizumab from aflibercept for eyes with nAMD with resistance to bimonthly injections of aflibercept is a valuable treatment option with and without the loading regimen. This trial is registered with UMIN000023676.

Keyphrases

age related macular degeneration
study protocol
clinical trial
optical coherence tomography
randomized controlled trial
phase ii
ultrasound guided
combination therapy
smoking cessation
double blind