lncRNA SNHG15 as a ceRNA modulates Osteoclast Differentiation, Proliferation, and Metastasis by Sponging miR-381-3p/NEK2 Axis.

YiFan Wang GuanYin Zhu Fang Pei ZhiHe Zhao

Published in: Journal of immunology research (2022)

SNHG15 acted as a ceRNA promoted the proliferation, migration, and differentiation of THP-1 cells induced by M-CSF/RANKL through sponging miR-381-3p to promote the expression of NEK2.

Keyphrases

poor prognosis
long non coding rna
signaling pathway
induced apoptosis
bone loss
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
cell death
nuclear factor
inflammatory response
long noncoding rna
toll like receptor