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Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma.

Cristoforo SimonettoMichael MayingerThamer AhmedKai BormPavel KundrátSteffi PigorschJan Christian KaiserStephanie E Combs
Published in: Radiation oncology (London, England) (2020)
Our study confirmed the thickening of artery walls and the increase in the number of plaques. Results imply that definitive radiation damage to the artery walls can be determined not earlier than about one year after radiotherapy and there is no substantial deterioration thereafter. Reasons for the absence of an observable intima media thickening in patients with diabetes are unclear.
Keyphrases
  • locally advanced
  • early stage
  • radiation induced
  • photodynamic therapy
  • oxidative stress
  • radiation therapy
  • squamous cell carcinoma
  • cross sectional
  • cardiovascular disease
  • bone marrow
  • mesenchymal stem cells