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Recent green approaches for the synthesis of pyrazolo[3,4-d]pyrimidines: A mini review.

Mai MaherAshraf F ZaherZeinab MahmoudAsmaa E Kassab
Published in: Archiv der Pharmazie (2022)
Pyrazolo[3,4-d]pyrimidine as a bioisostere of purine has drawn considerable attention as a privileged scaffold for the design and discovery of novel drugs. Green synthesis is an emerging area in the field of chemistry that provides economic and environmental benefits as an alternative to traditional methods. The present mini review reflects recent advances in the green synthesis of pyrazolo[3,4-d]pyrimidines, published in the time frame from 2006 to 2019.
Keyphrases
  • small molecule
  • working memory
  • systematic review
  • randomized controlled trial
  • risk assessment