Homeostasis model assessment of insulin resistance and outcome of ischemic stroke in non-diabetic patients - a prospective observational study.
Daniel ÅbergN David ÅbergKatarina JoodLukas HolmegaardPetra RedforsChristian BlomstrandJörgen IsgaardChristina JernJohan SvenssonPublished in: BMC neurology (2019)
In non-diabetic IS patients, HOMA-IR was elevated and related to stroke severity, but after adjustment for IS severity, the associations between HOMR-IR and poor outcome lost significance. This could suggest that elevated IR mostly is a part of the acute IS morbidity. However, in the subgroup of cryptogenic stroke, the associations with poor outcome withstood correction for stroke severity.
Keyphrases
- atrial fibrillation
- insulin resistance
- end stage renal disease
- type diabetes
- ejection fraction
- newly diagnosed
- chronic kidney disease
- liver failure
- metabolic syndrome
- adipose tissue
- cerebral ischemia
- randomized controlled trial
- clinical trial
- patient reported outcomes
- polycystic ovary syndrome
- skeletal muscle
- intensive care unit
- respiratory failure
- brain injury
- hepatitis b virus
- acute respiratory distress syndrome
- wound healing
- high fat diet induced