Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.
Hans-Christoph DienerCharly GaulWalter LehmacherThomas WeiserPublished in: European journal of neurology (2021)
Results showed that APC is superior to placebo in the treatment of acute migraine attacks. Efficacy, measured by pain-free response and pain relief at 2 h, was clinically relevant.
Keyphrases
- placebo controlled
- double blind
- liver failure
- chronic pain
- drug induced
- phase iii
- pain management
- respiratory failure
- liver injury
- low dose
- clinical trial
- open label
- randomized controlled trial
- squamous cell carcinoma
- type diabetes
- coronary artery disease
- hepatitis b virus
- combination therapy
- aortic dissection
- study protocol
- rectal cancer
- phase ii study
- mechanical ventilation
- acute respiratory distress syndrome