Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform.
Marc van VijvenBart van GroningenJoyce N KimenaiMaria C van der SteenMarina van DoeselaarRob P A JanssenKeita ItoJasper FoolenPublished in: Journal of experimental orthopaedics (2020)
The presented micro-tissue platform exposed patient-specific remodeling-related differences between tendon-derived cells, with the micro-tissues that released from constraining posts and pro-collagen I expression best reflecting the clinical age-dependency of graft rupture. These properties can be the starting point in the quest for potential predictors for identifying individual patients at risk for graft rupture.
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