Clinical relevance of cortical network dynamics in early primary progressive MS.

Carmen TurBaris KanberArman EshaghiDan R AltmannZhaleh KhaleeliFerran PradosSebastian OurselinAlan J ThompsonClaudia Am Gandini Wheeler-KingshottAhmed T ToosyOlga Ciccarelli

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2019)

SCNs are abnormal in early PPMS. Longitudinal SCN changes demonstrated a switch from low- to high-efficiency networks especially among fast progressors, indicating their clinical relevance.

Keyphrases

high efficiency
multiple sclerosis
mass spectrometry
cross sectional
network analysis