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Deoxycholic acid enhancement of lymphocyte migration through direct interaction with the intestinal vascular endothelium.

Naoki ShibuyaMasaaki HigashiyamaYoshihiro AkitaKazuhiko ShirakabeSuguru ItoShin NishiiAkinori MizoguchiKenichi InabaRina TanemotoNao SugiharaYoshinori HanawaAkinori WadaKazuki HoriuchiKenichi YoshikawaChie KuriharaYoshikiyo OkadaChikako WatanabeShunsuke KomotoKengo TomitaMasayuki SarutaRyota Hokari
Published in: Journal of gastroenterology and hepatology (2021)
DCA exacerbated IND-induced small intestinal enteropathy. DCA directly acts on the vascular endothelium and enhances the expression levels of adhesion molecules partially via S1PR2, leading to enhanced small intestinal lymphocyte migration.
Keyphrases
  • nitric oxide
  • peripheral blood
  • poor prognosis
  • high glucose
  • diabetic rats
  • oxidative stress
  • binding protein
  • biofilm formation
  • long non coding rna
  • escherichia coli
  • staphylococcus aureus