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Tracheal polypoid combined small cell lung cancer (C-SCLC): A case report.

Alberto TestoriGiorgio FerraroliCamilla De CarloPaola BossiMarco AlloisioGiuseppe Mangiameli
Published in: Thoracic cancer (2021)
Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis that accounts for 10% of all cases of clinical lung cancer. Due to its high growth fraction and rapid doubling time it is usually diagnosed as extensive local or metastatic disease in 60%-70% of cases. Combined small cell lung cancer (C-SCLC) is a relatively rare subtype of SCLC and is defined as SCLC combined with any elements of non-small cell lung cancer (NSCLC). Clinical presentation of SCLC as an isolated pedunculated endotracheal lesion is an especially rare occurrence. Here, we report for the first time the occurrence of a C-SCLC as a polypoid tumor of the trachea diagnosed in an 80-year-old woman admitted to the emergency department with a principal complaint of cough and wheezing.
Keyphrases
  • small cell lung cancer
  • poor prognosis
  • emergency department
  • brain metastases
  • risk assessment
  • long non coding rna
  • squamous cell carcinoma
  • tyrosine kinase