Bowenoid papulosis unveiling a rare cause of immunosuppression.
Betsy AmbookenN AsokanPrizey PhilipK T JishaPublished in: International journal of STD & AIDS (2019)
Bowenoid papulosis (BP) is a premalignant condition usually caused by oncogenic types of human papillomavirus (HPV) presenting clinically as warty genital papules. Adult T-cell leukaemia-lymphoma (ATLL) is a peripheral T-cell leukaemia-lymphoma caused by the retrovirus, human T-cell lymphotropic virus 1 (HTLV-1). We report a case of BP initially mistaken as genital warts; on detailed evaluation the patient had features of chronic immunosuppression. The presence of leukaemic cells in the peripheral blood, bone marrow and skin along with a positive HTLV-1 serology confirmed the diagnosis of ATLL.
Keyphrases
- peripheral blood
- bone marrow
- diffuse large b cell lymphoma
- case report
- induced apoptosis
- endothelial cells
- cell cycle arrest
- mesenchymal stem cells
- high grade
- induced pluripotent stem cells
- soft tissue
- transcription factor
- endoplasmic reticulum stress
- pluripotent stem cells
- oxidative stress
- cell proliferation
- cervical cancer screening
- childhood cancer