Obesity paradox in patients with non-small cell lung cancer undergoing immune checkpoint inhibitor therapy.
Ji Hyun LeeTae-Seok SeoJin Seok AhnEliseo GuallarJuhee ChoHo Yun LeePublished in: Journal of cachexia, sarcopenia and muscle (2023)
In Asian patients with advanced non-small cell lung cancer who received immune checkpoint inhibitors, obese BMI was associated with favourable overall survival independent of skeletal muscle or visceral fat mass.
Keyphrases
- advanced non small cell lung cancer
- insulin resistance
- adipose tissue
- skeletal muscle
- metabolic syndrome
- epidermal growth factor receptor
- weight loss
- high fat diet induced
- type diabetes
- weight gain
- body mass index
- obese patients
- fatty acid
- free survival
- tyrosine kinase
- stem cells
- replacement therapy
- smoking cessation