T-DM1 efficacy in trastuzumab-pertuzumab pre-treated HER2 positive metastatic breast cancer patients: a meta-analysis.

Claudia OmariniFederico PiacentiniIsabella SperdutiKrisida CermaMonica BarboliniFabio CaninoCecilia NassoChristel IscaFederica CaggiaMassimo DominiciLuca Moscetti

Published in: BMC cancer (2022)

Overall, the efficacy of T-DM1 after TP seems to be similar to that previously reported in the EMILIA trial. In the second line setting, data are not mature enough to confirm T-DM1 efficacy in TP pre-treated population.

Keyphrases

epidermal growth factor receptor
small cell lung cancer
squamous cell carcinoma
clinical trial
type diabetes
randomized controlled trial
big data
newly diagnosed
phase iii
phase ii
tyrosine kinase
weight loss
open label