Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis.
Andreas GroßeBirgit PernerUta NaumannChristoph EnglertPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)
Our data show that members of the zebrafish wtx/amer gene family, while sharing a partially overlapping expression pattern do not compensate for each other. This observation demonstrates a remarkable robustness during development and regeneration in zebrafish.