Pneumomediastinum in COVID-19: a phenotype of severe COVID-19 pneumonitis? The results of the United Kingdom (POETIC) survey.
James MelhornAndrew AchaiahFrancesca M ConwayElizabeth M F ThompsonErik W SkyllbergJoseph DurrantNeda A HasanYasser MadaniPrasheena NaranBavithra VijayakumarMatthew J TateGareth E TrevelyanIrfan ZakiCatherine A DoigGeraldine LynchGill WarwickAvinash AujayebKarl A JacksonHina IftikharJonathan H NobleAnthony Y K C NgMark NugentPhilip J EvansRobert A HastingsHarry R BellenbergHannah LawrenceRachel L SavilleNikolas T JohlAdam N GreyHuw C EllisCheng ChenThomas L JonesNadeem MaddekarShahul Leyakathali KhanAmbreen Iqbal MuhammadHakim GhaniYadee Maung Maung MyintCecillia RafiqueBenjamin J PippardBenjamin R H IrvingFawad AliViola H AsimbaAqeem AzamEleanor C BartonMalvika BhatnagarMatthew P BlackburnKate J MillingtonNicholas J BudhramKatherine L BunclarkToshit P SapkalGiles DixonAndrew J E HarriesMohammad IjazVijayalakshmi KarunanithiSamir NaikMalik Aamaz KhanKarishma SavlaniVimal KumarBeatriz Lara GallegoNoor A MahdiCaitlin MorganNeena PatelElen W RowlandsMatthew S StewardRichard S ThorleyRebecca L WollertonSana UllahDavid M SmithWojciech LasonAnthony J RostronNajib M RahmanRob J HallifaxPublished in: The European respiratory journal (2022)
Pneumomediastinum appears to be a marker of severe COVID-19 pneumonitis. The majority of patients in whom pneumomediastinum was identified had not been mechanically ventilated at the point of diagnosis.