Comparison of the Effective Reproduction Number (Rt) Estimation Methods of COVID-19 Using Simulation Data Based on Available Data from Iran, USA, UK, India, and Brazil.

The important result of this study is that TD and ML methods lead to a more accurate estimation of Rt of population than other methods. Therefore, in order to monitor and determine the epidemic situation and have a more accurate prediction of the incidence rate, as well as control COVID-19 and similar diseases, the use of these two methods is suggested to more accurately estimate Rt.