Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial.
Marcia Waddington-CruzElizabeth J AckermannMichael PolydefkisStephen B HeitnerPeter J DyckFabio A BarrosoAnnabel K WangJohn L BerkP James B DyckBrett P MoniaSteven G HughesLi TaiT Jesse KwohShiangtung W JungTeresa CoelhoMerrill D BensonMorie A GertzPublished in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2018)
Baseline data from the NEURO-TTR trial demonstrates ATTRm amyloidosis as a systemic disease with deficits in multiple organs and body systems, leading to decreased quality of life. We report concomitant presentation of polyneuropathy and cardiomyopathy in most patients, and early involvement of multiple body systems.