The RNA-binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA.
Li-Li HanChen HuangShuqun ZhangPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
In this study, we found for the first time that SORBS2 contributed to the suppression of HCC tumourigenesis and metastasis via post-transcriptional regulation of RORA expression as an RBP.