A nano particle vector comprised of poly lactic-co-glycolic acid and monophosphoryl lipid A and recombinant Mycobacterium avium subsp paratuberculosis peptides stimulate a pro-immune profile in bovine macrophages.
C D SouzaJ P BannantineW C BrownM G NortonW C DavisJ K HwangP ZiaeiGaber S AbdellrazeqM V ErenJ R DeringerE LawsM C D CardieriPublished in: Journal of applied microbiology (2017)
These results will assist on more in depth studies on PLGA NP delivery systems that may lead to the development of a peptide-based vaccine for cattle.