Cerebrospinal fluid lipidomics: effects of an intravenous triglyceride infusion and apoE status.

Angela J HansonWilliam A BanksLisa F BettcherRobert PepinDaniel RafterySuzanne Craft

Published in: Metabolomics : Official journal of the Metabolomic Society (2019)

These results in older adults show that blood lipids affect lipid profiles in CSF and such profiles are modified by APOE status. This suggests that how the CNS handles lipids may be important in the AD phenotype.

Keyphrases

cerebrospinal fluid
cognitive decline
fatty acid
high fat diet
physical activity
low dose
high dose
mild cognitive impairment
adipose tissue