Factors associated with the onset of major depressive disorder in adults with type 2 diabetes living in 12 different countries: results from the INTERPRET-DD prospective study.

Cathy E LloydN SartoriusH U AhmedA AlvarezS BahendekaA E BobrovL BurtiS K ChaturvediW GaebelG de GirolamoT M GondekM GuinzbourgM G HeinzeA KhanA KiejnaA KokoszkaT KamalaN M LalicD Lecic-TosevskiE MannucciB MankovskyK MüssigV MutisoD NdeteiA NouwenG RabbaniS S SrikantaE G StarostinaM ShevchukR TajU ValentiniK van DamO VukovicW Wölwer

Published in: Epidemiology and psychiatric sciences (2020)

This study demonstrates the importance of psychosocial factors in addition to physiological variables in the development of depressive symptoms and incident MDD in people with type 2 diabetes. Stressful life events, depressive symptoms and diabetes-related distress all play a significant role which has implications for practice. A more holistic approach to care, which recognises the interplay of these psychosocial factors, may help to mitigate their impact on diabetes self-management as well as MDD, thus early screening and treatment for symptoms is recommended.

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