SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial-mesenchymal transition and mitochondrial function maintenance.

Jiafeng ChenZheng GaoXiaogang LiYing-Hong ShiZheng TangWeiren LiuXin ZhangAo HuangXuanming LuoQiang GaoGuangyu DingKang SongJian Zhou Jia FanXiutao FuZhenbin Ding

Published in: Cancer medicine (2022)

These data provided new evidence for the mechanism by which abundant p62 expression promoted ICC progression, suggesting a promising therapeutic target for antimetastatic strategies in patients with ICC.

Keyphrases

poor prognosis
epithelial mesenchymal transition
long non coding rna
transforming growth factor
electronic health record
signaling pathway
big data
binding protein
artificial intelligence