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Human platelet lysate enhances in vivo activity of CAR-Vδ2 T cells by reducing cellular senescence and apoptosis.

Feiyan MoChiou-Tsun TsaiRong ZhengChonghui ChengHelen E HeslopMalcolm K BrennerMaksim MamonkinNorihiro Watanabe
Published in: Cytotherapy (2024)
This study supports enhancement of therapeutic potency of CAR-Vδ2 T cells through a manufacturing improvement.
Keyphrases
  • endothelial cells
  • oxidative stress
  • cell death
  • dna damage
  • cell cycle arrest
  • pluripotent stem cells
  • signaling pathway
  • pi k akt