Intermuscular adipose tissue in patients with systemic lupus erythematosus.

Jorge Luis GamboaDaniel Carranza-LeónRachelle CrescenziMichael PridmoreDungeng PengAdriana MartonAnnette OeserCecilia P ChungJens TitzeCharles Michael SteinMichelle Ormseth

Published in: Lupus science & medicine (2022)

Patients with SLE have greater IMAT accumulation than controls in the calf muscles. Increased IMAT is associated with greater fatigue and lower physical activity. Future studies should evaluate the effectiveness of interventions that improve muscle quality to alleviate fatigue in patients with SLE.

Keyphrases

physical activity
systemic lupus erythematosus
sleep quality
adipose tissue

disease activity
randomized controlled trial
systematic review
skeletal muscle

insulin resistance
current status
body mass index
high fat diet

case control
depressive symptoms
quality improvement
metabolic syndrome