Impact of immunosuppressive therapy on SARS-CoV-2 mRNA vaccine effectiveness in patients with immune-mediated inflammatory diseases: a Danish nationwide cohort study.

Rahma Elmahdi Daniel J WardMartin T ErnstGry Juul Poulsen Nina Sahlertz Kristiansen Jesper Hallas Tine Jess

Published in: BMJ open (2024)

Immunosuppressive therapies reduced effectiveness of mRNA SARS-CoV-2 vaccination against infection and hospitalisation in patients with IMID. Anti-TNF, systemic corticosteroids, and rituximab and other immunosuppressants were particularly associated with these risks.

Keyphrases

sars cov
randomized controlled trial
respiratory syndrome coronavirus
systematic review
rheumatoid arthritis
binding protein
diffuse large b cell lymphoma
oxidative stress
human health
hodgkin lymphoma
stem cells
climate change