Enhancement of Inhibitory Activity by Combining Allosteric Inhibitors Putatively Binding to Different Allosteric Sites on Cathepsin K.
Shun SatoKana YamamotoMoeno ItoKatsutoshi NishinoTakanao OtsukaKazuhiro IrieMasaya NagaoPublished in: Molecules (Basel, Switzerland) (2023)
Different allosteric inhibitors that bind to different sites in combination, as shown in this study, may be useful for designing new allosteric inhibitory drugs with high specificity and few side effects.
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