HLA expression as a risk factor for metastases of cutaneous squamous-cell carcinoma in organ- transplant recipients.
Estella de JongKoen D QuintAbdoelwaheb El GhalbzouriRobert M VerdijkJelle J GoemanSebastiaan HeidtFrans H J ClaasJohan W de FijterRoel E GendersMaarten H VermeerJan Nico Bouwes BavinckPublished in: Human immunology (2023)
Contrary to immunocompetent patients, HLA-B/C expression tends to be upregulated in metastasized cSCC compared to non-metastasized cSCC in SOTR, suggesting that different tumor escape mechanisms play a role in SOTR compared to immunocompetent patients.