The Oral Glucose Tolerance Test-Is It Time for a Change?-A Literature Review with an Emphasis on Pregnancy.
Delia BogdanetPaula M O'SheaClaire LyonsAmir ShafatFidelma P DunnePublished in: Journal of clinical medicine (2020)
Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impact on the future health of generations through the long-term impact of GDM on both mothers and their infants. Therefore, correctly identifying subjects as having GDM is of utmost importance. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy.
Keyphrases
- pregnancy outcomes
- type diabetes
- global health
- public health
- pregnant women
- insulin resistance
- preterm birth
- healthcare
- metabolic syndrome
- case report
- mental health
- cardiovascular disease
- polycystic ovary syndrome
- weight loss
- risk factors
- glycemic control
- body mass index
- health information
- physical activity
- current status