Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial.

Nicholas M BarbaroMark QuiggMariann M WardEdward F ChangDonna K BroshekJohn T LangfittGuofen YanKenneth D LaxerAndrew J ColePenny K SneedChristopher P HessWei YuManjari TripathiChristianne N HeckJohn W MillerPaul A GarciaAndrew McEvoyNathan B FountainVincenta SalanovaRobert C KnowltonAnto BagićThomas HenrySiddharth KapoorGuy McKhannAdriana E PaladeMarkus ReuberEvelyn Tecoma

Published in: Epilepsia (2018)

These data suggest that ATL has an advantage over SRS in terms of proportion of seizure remission, and both SRS and ATL appear to have effectiveness and reasonable safety as treatments for MTLE. SRS is an alternative to ATL for patients with contraindications for or with reluctance to undergo open surgery.

Keyphrases

temporal lobe epilepsy
minimally invasive
coronary artery bypass
phase iii
phase ii
open label
randomized controlled trial
clinical trial
double blind
surgical site infection
systematic review
study protocol
placebo controlled
electronic health record
big data
brain metastases
acute coronary syndrome
deep learning