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Impact of heart rate variability, a marker for cardiac health, on lupus disease activity.

Aikaterini ThanouStavros StavrakisJohn W DyerMelissa E MunroeJudith A JamesJoan T Merrill
Published in: Arthritis research & therapy (2016)
Impaired HRV, particularly the LF/HF ratio, is associated with lupus disease activity and several cytokines related to IFN type II and TNF pathways. The strongest association was with MIG and sTNFRII, expanding previous immune connections of vagal signaling.
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