Effect of Tertiary Lymphoid Structures on Prognosis of Patients with Hepatocellular Carcinoma and Preliminary Exploration of Its Formation Mechanism.

Jianhui LiYe NieWeili JiaWenlong WuWenjie SongYongxiang Li

Published in: Cancers (2022)

TLSs mainly affected the early RFS of HCC patients but had no effect on OS. The high expression of the TLS formation-related gene LCK can increase the sensitivity of HCC patients to ICIs.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
poor prognosis
prognostic factors
gene expression
high resolution
dna methylation
long non coding rna
transcription factor