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Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production.
Parisa Moradbeigi
Sara Hosseini
Mohammad Salehi
Asghar Mogheiseh
Published in:
Biological procedures online (2024)
Overall, this study highlights the significant potential of the MBCD-SMGE technique for generating targeted mutant mice. It holds enormous promise for modeling human diseases and improving desirable traits in animals.
Keyphrases
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wild type
cancer therapy
endothelial cells
genome wide
big data
induced pluripotent stem cells
high fat diet induced
type diabetes
pluripotent stem cells
metabolic syndrome
machine learning
risk assessment
skeletal muscle
ionic liquid
capillary electrophoresis
artificial intelligence