Meta-analytic evidence for increased low-grade systemic inflammation and oxidative stress in hypothyroid patients. Can levothyroxine replacement therapy mitigate the burden?
Mariana L TellecheaPublished in: Endocrine (2020)
Overall, these meta-analyses reveal that screening for hs-CRP and MDA in hypothyroid patients as simple biomarkers of low-grade systemic inflammation and oxidative stress may become a useful tool to identify those at increased risk who may benefit most from early interventions.
Keyphrases
- low grade
- oxidative stress
- end stage renal disease
- high grade
- newly diagnosed
- ejection fraction
- replacement therapy
- chronic kidney disease
- systematic review
- prognostic factors
- randomized controlled trial
- dna damage
- peritoneal dialysis
- physical activity
- gene expression
- meta analyses
- risk factors
- genome wide
- cell proliferation
- single cell
- induced apoptosis