Novel selective agonist of GPR18, PSB-KK-1415 exerts potent anti-inflammatory and anti-nociceptive activities in animal models of intestinal inflammation and inflammatory pain.
Adam FabisiakNatalia FabisiakAnna MokrowieckaEwa Malecka-PanasDamian JacenikRadzislaw KordekMarta ZielinskaKatarzyna Kieć-KononowiczJakub FichnaPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
We showed that GPR18 is worth considering as a potential treatment target in intestinal inflammation and inflammatory pain.