Metabolic reprogramming by HIF-1 activation enhances survivability of human adipose-derived stem cells in ischaemic microenvironments.

Chang ChenQi TangYan ZhangMinjia DaiYichen JiangHang WangMei YuWei JingWeidong Tian

Published in: Cell proliferation (2017)

The promotion of HIF-1 level in ADSCs induced by DMOG preconditioning suggests a potential strategy for improving the outcome of cell therapy due to increased survival and angiogenic ability.

Keyphrases

cell therapy
endothelial cells
stem cells
mesenchymal stem cells
induced pluripotent stem cells
pluripotent stem cells
free survival
human health
cerebral ischemia
oxidative stress
climate change