Phase 1 study of NEDD8 activating enzyme inhibitor pevonedistat in combination with chemotherapy in pediatric patients with recurrent or refractory solid tumors (ADVL1615).

Jennifer H FosterJoel M ReidCharles MinardSarah WoodfieldKristina Z DenicEmasenyie IsikweiStephan D VossMarvin NelsonXiaowei LiuStacey L BergElizabeth FoxBrenda J Weigel

Published in: European journal of cancer (Oxford, England : 1990) (2024)

on days 1, 3, 5 in combination with IRN/TMZ.

Keyphrases

signaling pathway
open label
locally advanced
randomized controlled trial
squamous cell carcinoma
double blind