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Phase 1 study of NEDD8 activating enzyme inhibitor pevonedistat in combination with chemotherapy in pediatric patients with recurrent or refractory solid tumors (ADVL1615).

Jennifer H FosterJoel M ReidCharles MinardSarah WoodfieldKristina Z DenicEmasenyie IsikweiStephan D VossMarvin NelsonXiaowei LiuStacey L BergElizabeth FoxBrenda J Weigel
Published in: European journal of cancer (Oxford, England : 1990) (2024)
on days 1, 3, 5 in combination with IRN/TMZ.
Keyphrases
  • signaling pathway
  • open label
  • locally advanced
  • randomized controlled trial
  • squamous cell carcinoma
  • double blind