Genome-wide Association Study and Meta-analysis on Alcohol-Associated Liver Cirrhosis Identifies Genetic Risk Factors.
Tae-Hwi Schwantes-AnRebecca DarlayPhilippe MathurinSteven MassonSuthat LiangpunsakulSebastian MuellerGuruprasad P AithalFlorian EyerDermot GleesonAndrew ThompsonBeat MuellhauptFelix StickelMichael SoykaDavid GoldmanTiebing LiangLawrence LumengMunir PirmohamedBertrand NalpasJean-Marc JacquetRomain MoirandPierre NahonSylvie NaveauPascal PerneyGreg BotwinPaul S HaberHelmut K SeitzChristopher P DayTatiana M ForoudAnn K DalyHeather J CordellJohn B WhitfieldTimothy R MorganDevanshi Sethnull nullPublished in: Hepatology (Baltimore, Md.) (2022)
Our genetic findings implicate lipid droplets in the biological pathway(s) underlying ALC.