Login / Signup

Pharmacokinetics/pharmacodynamics of benralizumab in chronic rhinosinusitis with nasal polyps: Phase III, randomized, placebo-controlled OSTRO trial.

Claire EmsonJoseph K HanClaire HopkinsSara AsimusJennifer A CannDavid ChainYuling WuYasa ReddyChristopher McCraeDavid CohenJames L KreindlerViktoria WerkströmMaria JisonMartin WagenmannClaus Bachert
Published in: British journal of clinical pharmacology (2024)
Benralizumab treatment led to rapid, sustained, nearly complete depletion of eosinophils from blood and nasal polyp tissue in patients with CRSwNP.
Keyphrases
  • chronic rhinosinusitis
  • phase iii
  • placebo controlled
  • double blind
  • open label
  • phase ii
  • clinical trial
  • study protocol
  • phase ii study
  • randomized controlled trial
  • combination therapy
  • replacement therapy