Dendritic spines provide cognitive resilience against Alzheimer's disease.

Benjamin D BorosKelsey M GreathouseErik G GentryKendall A CurtisElizabeth L BirchallMarla GearingJeremy H Herskowitz

Published in: Annals of neurology (2017)

These observations provide cellular evidence to support the hypothesis that dendritic spine plasticity is a mechanism of cognitive resilience that protects older individuals with AD pathology from developing dementia. Ann Neurol 2017;82:602-614.

Keyphrases

climate change
social support
mild cognitive impairment
cognitive decline
physical activity
cognitive impairment
community dwelling
neural network