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Influence of the aldehyde dehydrogenase 2 polymorphism on the vasodilatory effect of nitroglycerin in infants with congenital heart disease and pulmonary arterial hypertension.

Tatsuya NaganoKentaro UshijimaNaoyuki TagaMamoru TakeuchiMasa-Aki KawadaKenichi AizawaYasushi ImaiAkio Fujimura
Published in: European journal of clinical pharmacology (2019)
These data suggest that the ALDH2 gene polymorphism influences the pharmacokinetics and haemodynamics of GTN in human subjects.
Keyphrases
  • pulmonary arterial hypertension
  • pulmonary artery
  • pulmonary hypertension
  • endothelial cells
  • induced pluripotent stem cells
  • electronic health record
  • pluripotent stem cells
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  • coronary artery
  • data analysis