Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial.
Aung MyatSimon R RedwoodSatpal ArriBernard J GershDeepak L BhattMichael S MarberPublished in: Diabetology & metabolic syndrome (2021)
Liraglutide did not enhance exercise tolerance or haemodynamics compared with saline placebo during serial treadmill testing in patients with established obstructive CAD. It did, however, significantly reduce weight and improve the lipid profile. Trial Registration ClinicalTrials.gov Identifier NCT02315001. Retrospectively registered on 11th December 2014.
Keyphrases
- placebo controlled
- phase iii
- double blind
- phase ii
- study protocol
- open label
- clinical trial
- coronary artery disease
- physical activity
- high intensity
- phase ii study
- body mass index
- coronary artery
- randomized controlled trial
- resistance training
- atrial fibrillation
- squamous cell carcinoma
- body composition
- radiation therapy
- aortic valve
- aortic stenosis
- cone beam