Aronia (Aronia melanocarpa) Polyphenols Modulate the Microbial Community in a Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and Decrease Secretion of Proinflammatory Markers in a Caco-2/endothelial Cell Coculture Model.

Ting WuCharlotte GrootaertJudit PitartNevena Kardum VidovicSenem KamilogluSam PossemiersMaria GlibeticGuy SmaggheKatleen RaesTom Van de WieleJohn Van Camp

Published in: Molecular nutrition & food research (2018)

Aronia polyphenols modulate intestinal microbial composition, induce beneficial short chain fatty acid production, and prevent inflammatory stress in endothelial cells. This opens perspectives for the use of Aronia polyphenols as prebiotics in the context of intestinal and cardiovascular health.

Keyphrases

microbial community
endothelial cells
antibiotic resistance genes
high glucose
fatty acid
vascular endothelial growth factor
oxidative stress
induced pluripotent stem cells
virtual reality
wastewater treatment