Seven key hub genes identified by gene co-expression network in cutaneous squamous cell carcinoma.

Huizhen ChenJian-Kang YangWenjuan Wu

Published in: BMC cancer (2021)

We applied WGCNA to find seven hub genes that play important roles in cSCC tumorigenesis. These results provide new insights that help explain the pathogenesis of cSCC. These hub genes may become biomarkers or therapeutic targets for accurate diagnosis and treatment of cSCC in the future.

Keyphrases

bioinformatics analysis
genome wide
genome wide identification
squamous cell carcinoma
network analysis
poor prognosis
genome wide analysis
transcription factor
high resolution
dna methylation
current status
gene expression
lymph node metastasis