The Role of testosterone treatment in patients with metabolic disorders.
Giovanni CoronaGiulia RastrelliLinda VignozziArcangelo BarbonettiAlessandra SforzaEdoardo MannucciMario MaggiPublished in: Expert review of clinical pharmacology (2021)
Data derived from preclinical and clinical studies suggest that T administration, by reducing fat mass, can improve body composition and ameliorate some aspects of glucose metabolism. The effects of TRT on sexual function in patients with established metabolic derangements are inconsistent, whereas better results were observed in preclinical conditions or in patients with newly diagnosed T2DM.