Exploring the role of the ovary-serine protease gene in the female fertility of the diamondback moth using CRISPR/Cas9.

Muhammad AsadJianying LiaoJing ChenFaisal MunirSenbo PangAnam Noreen AbbasGuang Yang

Published in: Pest management science (2024)

Our study suggesteds that PxOsp plays a vital role in female reproduction, particularly in ovary and egg development. Disrupting PxOsp results in recessive female sterility while leaving the male reproductive capability unaffected. This report represents the first study of a haplosufficient gene responsible for female fertility in lepidopteran insects. Additionally, these findings emphasize PxOsp as a potential target for genetically-based pest management of P. xylostella. © 2024 Society of Chemical Industry.

Keyphrases

crispr cas
copy number
genome wide
genome editing
gene expression
autism spectrum disorder
intellectual disability
young adults
climate change