Clinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses.
Jack BrzezinskiSanaa ChoufaniRodrigo RomaoCheryl ShumanHaiying ChenJoanna CunananDarius BagliRonald GrantArmando LorenzoRosanna WeksbergPublished in: British journal of cancer (2020)
We have identified subgroup-specific molecular events that could inform future work supporting more targeted therapeutic approaches and patient stratification. We propose a novel developmental tumour model based on these findings.