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Clinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses.

Jack BrzezinskiSanaa ChoufaniRodrigo RomaoCheryl ShumanHaiying ChenJoanna CunananDarius BagliRonald GrantArmando LorenzoRosanna Weksberg
Published in: British journal of cancer (2020)
We have identified subgroup-specific molecular events that could inform future work supporting more targeted therapeutic approaches and patient stratification. We propose a novel developmental tumour model based on these findings.
Keyphrases
  • case report
  • current status
  • cancer therapy
  • copy number
  • randomized controlled trial
  • dna methylation
  • drug delivery
  • genome wide
  • study protocol