Hyperoxia and antioxidants during major non-cardiac surgery and risk of cardiovascular events: Protocol for a 2 × 2 factorial randomised clinical trial.

Cecilie Petersen Frederik C Loft Eske Kvanner Aasvang Morten Vester-Andersen Lars Simon Rasmussen Jorn Wetterslev Lars Nannestad Jørgensen Robin Christensen Christian Sahlholt Meyhoff

Published in: Acta anaesthesiologica Scandinavica (2019)

The current trial will provide further evidence for clinicians on optimal administration of perioperative oxygen in surgical patients with cardiovascular risks and the clinical effects of two common antioxidants.

Keyphrases

cardiovascular events
clinical trial
cardiac surgery
study protocol
phase ii
phase iii
open label
acute kidney injury
coronary artery disease
cardiovascular disease
double blind
randomized controlled trial
palliative care
human health
patients undergoing
risk assessment
placebo controlled
climate change