Fetal lung development via quantitative biomarkers from diffusion MRI and histological validation in rhesus macaques.

Nara S HiganoXuefeng CaoJinbang GuoXiaojie WangChristopher D KroenkeAlyssa L FilutaJames P BridgesJason C Woods

Published in: Journal of perinatology : official journal of the California Perinatal Association (2021)

Fetal DW-MRI provides a non-invasive biomarker for pulmonary structural maturation, with a strong correlation to histological markers during tissue development in rhesus macaques. This method has strong potential for assessing human fetal development, particularly in patients with pulmonary hypoplasia.

Keyphrases

magnetic resonance imaging
pulmonary hypertension
contrast enhanced
risk assessment
pluripotent stem cells